The Science behind
activating sertuins that
Ageing is our enemy. It saps our strength, cripples us, and eventually kills us. Yet people are largely unaware and uncaring of ongoing research into ageing and longevity, of the plausible future of rejuvenation bio-technologies, and even of how to make the most of health and longevity using the tools that have come to light over the past ten years of research.
Many people think that life expectancy is largely determined by genetics. However, genes play a much smaller role than originally believed. It turns out that environmental factors like diet and lifestyle are key, along with genetic scientific research.
David Sinclair PhD from Harvard Medical School says Mimicking with Molecules is not just as effective for longevity but even better than intermittent fasting.
Dr. David Sinclair is the leading world authority on genetics and longevity. The key to longevity is activating newly discovered vitality genes, the descendants of an ancient genetic survival circuit that is both the cause of ageing and the key to reversing it.
A set of genes that control ageing in yeast cells, genes called sirtuins, 7 of them in our body, 5 in yeast, they protect all organisms on the planet from deterioration and disease. They sense when we're hungry, when we're exercising and they send out the troops to defend us, so when you put more of these cells into a mouse it'll live up to 20% longer. The two molecules that increase NAD+ and activate sirtuins are NMN and Resveratrol. We lose NAD+ as we age and when you reach fifty you'll have half the levels of what you had when you were twenty.
Nicotinamide Mononucleotide boosts NAD+ levels in mice and activates sirtuins genes enabling old mice to once again run long distance (improving their endurance), repair blood vessels and make their muscles younger. Peter Attia, who included the NMN molecule showed she reduced her biological age by five years. In rodents, Resveratrol supplementation also decreased cardiovascular risk factors.
Recommended dosage: 50mg - 100mg per day.
David Sinclair PhD takes quite a high dosage:
Resveratrol – 1g/daily – mornings with bio yogurt, Nicotinamide Mononucleotide (NMN) 1g/daily
Compared to commonly used tablets, capsules and other oral dosage forms, sublingual absorption is generally much faster and more efficient. Peak blood levels of most products administered in a sublingual way are achieved within 10‐15 minutes, which is generally much faster than when those same compounds are ingested orally.
Per gram our prices are the lowest.
Trans-Resveratrol - is the accelerator pedal for the sirtuins genes and NMN is the fuel. Old theories about ageing, should be disregarded according to Dr. Sinclair. Free radicals, antioxidants, DNA damage, and mutations, is incorrect, antioxidants have failed in the anti-ageing world, Resveratrol is an antioxidant but doesn’t work like that in longevity, it steps on the accelerator pedal for sirtuins, so it’s directly controlling the bodies defences against ageing. A study by the University of Hong Kong found that Resveratrol increases the lifespan of the hair follicle. And further research by the University of Pennsylvania found that Resveratrol can help suppress a hormone called PDG2, which is linked to inhibited levels of hair growth. Reduces the instances or severity of the following: Liver disease Joint disease Alzheimer’s disease Lyme disease Parkinson’s disease Multiple sclerosis Atherosclerosis (hardened arteries) Molar mass 228.247 g·mol−1 Appearance white powder with slight yellow cast Melting point 261 to 263 °C (502 to 505 °F; 534 to 536 K) Solubility in water 0.03 g/L They are not all the same thing. Resveratrol is the general product name for a supplement sold in different levels of purity. Trans resveratrol, on the other hand, is the active ingredient in a resveratrol supplement.
Is eating Oats good for you?
Health Benefits of Eating Oats
Oats Are Incredibly Nutritious.
Whole Oats Are Rich in Antioxidants, Including Avenanthramides.
Oats Contain a Powerful Soluble Fiber Called Beta-Glucan.
They Can Lower Cholesterol Levels and Protect LDL Cholesterol From Damage.
Oats Can Improve Blood Sugar Control.
Oatmeal Is Very Filling and May Help You Lose Weight.
A bowl of porridge every day, say scientists. A small bowl of porridge each day could be the key to a long and healthy life, researchers have found. A major study of more than 100,000 people for more than 14 years found that whole grains reduce the risk of dying from heart disease.
AVOID common processed foods:
savoury snacks, such as crisps, sausage rolls, pies and pasties.
meat products, such as bacon, sausage, ham, salami and paté
microwave meals or ready meals.
cakes and biscuits.
Dr Gundry and Lectins. ARE LECTINS BAD FOR US?
Lectins are a family of proteins found in almost all foods, especially legumes and grains.
Dr Gundry claims that lectins cause increased gut permeability and drive autoimmune diseases. While it's true that certain lectins are toxic and cause harm when consumed in excess,Lectins are easy to get rid of through cooking, Dr Gundry suggests pressure cooking.
Foods highest in lectin include:
Nightshade vegetables, such as tomatoes (when you have tomatoes peel and take out the seeds), potatoes, goji berries, peppers, and eggplant.
All legumes, such as lentils, beans, peanuts, and chickpeas.
Peanut-based products, such as peanut butter and peanut oil.
Dr. Gundry suggests completely avoiding the following foods: corn. meat from corn-fed animals.
Foods to avoid;
Legumes, including beans, peas, lentils, and peanuts.
Nightshade vegetables, such as eggplant, peppers, potatoes, and tomatoes, grains
Fruit, although the diet allows moderate amounts of in-season fruit.
Dr Gundry recommends the following foods for people who wish to limit their lectin intake:
Foods that have low amounts of lectins are plentiful;
Onions, mushrooms, broccoli, bok choy, cauliflower, leafy greens, sweet potatoes, yams, carrots, asparagus, citrus fruits, apples, pears, blueberries.
Fish, seafood, eggs, olive oil, avocado, brussels sprouts, asparagus, garlic.
A2 milk, A1 and A2 milk contain different types of beta-casein protein. A2 Milk® is real milk from cows that naturally produce only the A2 protein and no A1. It should taste just like ordinary dairy milk but is considered to be a more healthy option.
Lectins break down when processed or cooked, so the risk of adverse health effects arising from lectin-rich foods that aren't raw is not cause for concern. In addition, most foods that contain lectins are recommended as part of a healthy, well-balanced diet.
A scientific balanced diet has proved to be the best, most beneficial way to maintain a healthy lifestyle.
Some researchers say Eat beans and live longer, maybe even live to 100. The researchers found that legumes were the most important dietary predictor of survival among the elderly, “regardless of their ethnicity,” they wrote. You'd have to eat about eight slices of whole-wheat bread to get the same amount of fibre.
DOES SUGAR CAUSE CANCER?
Sugar feeds every cell in your body. But does sugar cause cancer, or help it to grow and spread? Our expert says to watch out for added sugars, but not for the reasons you may think.
Does sugar “feed” cancer cells?
Let’s look at the evidence to find out whether sugar causes cancer to grow and spread more quickly.
It’s true that sugar feeds every cell in our body, even cancer cells. But, research shows that eating sugar doesn’t necessarily lead to cancer. It’s what sugar does to your waistline that can lead to cancer.
Taking in too many sugar calories may result in weight gain. And, being overweight or obese puts you at a higher risk for cancer and other diseases.
So, should you avoid sugar? Our expert says no.
“Your body’s cells use sugar to keep your vital organs functioning,” says Erma Levy, a research dietitian in Behavioral Science. “But too much daily sugar can cause weight gain. And, unhealthy weight gain and a lack of exercise can increase your cancer risks.”
Natural sugars, like molasses, agave nectar, honey and maple syrup, are packed with antioxidants that protect your body from cancer.
Here are some popular low-impact activities.
Home exercises. These are ideal if you're not very active but want to improve your health, lift your mood and remain independent.
Walking is by far the most popular low-impact exercise.
What is the healthiest exercise?
Aerobic exercises, such as running, swimming or dancing, are activities that work your cardiovascular system, they get your heart rate up and make you breathe harder. This type of exercise can reduce the risk of cardiovascular disease, type 2 diabetes and high blood pressure, and may even lower the risk of cancer.
How much should you walk a day?
The U.S. Department of Health and Human Services.
Physical Activity Guidelines for Americans recommends adults perform moderate-intensity aerobic exercise such as a brisk walk a minimum of 30 minutes, five days per week (or a total of 2 hours, 30 minutes) to reduce the risk of disease later in life.
Be careful when you come across various teaching that draw you in making huge claims and portraying misinformation. You’d be better off with the wide views of the scientific community across the world looking into longevity, and making this part of your every day routine.
SCIENTIFIC STEPS TO A LONGER LIFE
1. activate sertuins that regulate longevity with Resveratrol and NMN
2. never over sleep but get adequate sleep that suits you
3. a daily gentle walking routine
4. meditate to free your mind of busy activity
5. enjoy healthy food without over eating
6. eat a plant based diet
7. stay physically active
8. don't smoke
9. stillness meditation
10. abstain from food occasionally
11. don't drink too much alcohol
12. protect your skin from ultraviolet radiation
13. daily yoga stretching exercise
14. include turmeric in your diet
15. include blueberries in your diet
16. include Probiotic Yogurt in your diet
MEDITATION TECHNIQUES CD
MEALS THAT HEAL
Laqucia World LONGEVITY Foods
Watercress is a powerhouse vegetable that packs several important nutrients but is extremely low in calories. It contains a plethora of antioxidants, which will lower your risk of heart disease and several types of cancer. It's also a good source of minerals that protect your bones. Watercress is a good anti-cancer super-food. Eating watercress daily can significantly reduce DNA damage to blood cells, which is considered to be an important trigger in the development of cancer, University of Ulster scientists revealed today 15 February 2019
High Sugar Foods to have only occasionally, try to keep sugar content to a minimum
Yogurt containing high sugar content
Chocolate containing high sugar content
Fructose (sugar from fruits)
Lactose (sugar from milk)
Sucrose (made from fructose and glucose)
Maltose (sugar made from grain)
Glucose (simple sugar,)
Dextrose (form of glucose)
Heart disease. High-sugar diets may increase the risk of heart disease. The results of a 15-year study suggest that people with a lot of added sugar in their diet are significantly more likely to die from heart disease than people with minimal amounts of added sugar in their diet.
Juice with high sugar content
Avoid high sugar and check supermarket labels.
AVOID BAD SUGAR
Sugar Filled Drinks
Sugar Loaded Desserts
Processed Snack Foods
Sugar Filled Breakfast Foods
Sauces With Lots of Sugar
Prof Valter Longo PhD of Gerontology University of Southern California, Director of the institute of Longevity.
Research in America shows benefits from a fasting diet. There are different ways to fast, intermittent fasting is an increasingly popular eating pattern which involves not eating or sharply restricting your food intake for certain periods of time. This fasting method has been linked to a range of potential health benefits. Such effects are linked to longevity and a lower risk of disease. Thus, people who fast regularly often hope to lose weight and live a healthier, longer life.
1. Keep Fasting Periods Short
There is no single way to fast, meaning that the duration of your fast is up to you; however Prof of Gerontology University of Southern California, Valter Longo ph.D Director of the institute of Longevity in America suggests a fast mimicking diet does significantly lower the risk of disease in older aged people and can lengthen your life span, he has a website where you can learn more, even order a range of specialist products to help you.
2. Eat a Small Amount on Fast Days
In general, fasting involves the removal of some or all food and drink for a period of time.
Although you can remove food altogether on fast days, some fasting patterns allow you to consume up to around 25% of your calorie requirements in a day.
If you want to try fasting, restricting your calories so that you still eat small amounts on your fast days may be a safer option than doing a full-blown fast.
This approach may help reduce some of the risks associated with fasting, such as feeling faint, hungry and unfocused.
It may also make fasting more sustainable since you likely won’t feel as hungry.
3. Stay Hydrated
Mild dehydration can result in fatigue, dry mouth, thirst and headaches, so it’s vital to drink enough fluid on a fast.
Because you get around 20 to 30% of the fluid your body needs from food, it’s quite easy to get dehydrated while on a fast.
4. Go for Walks or Meditate
Avoiding eating on fast days can be difficult, especially if you are feeling bored and hungry.
One way to avoid unintentionally breaking your fast is to keep busy.
However, any activity that’s calming and not too strenuous would keep your mind engaged. You could read a book.
5. Don’t Break Fasts With a Feast
It can be tempting after a period of restriction to celebrate by eating a huge meal.
However, breaking your fast with a feast could leave you feeling bloated and tired.
Additionally, if you want to lose weight, feasting may harm your long-term goals by slowing down or halting your weight loss.
The best way to break a fast is to continue eating normally and get back into your regular eating routine.
6. Stop Fasting If You Feel Unwell
During a fast, you may feel a little tired, hungry and irritable, but you should never feel unwell.
To keep yourself safe, especially if you are new to fasting, consider limiting your fast periods to 24 hours or fewer and keeping a snack on hand in case you start to feel faint or ill.
If you do become ill or are concerned about your health, make sure you stop fasting straight away.
7. Eat Enough Protein
Many people start fasting as a way to try to lose weight.
However, being in a calorie deficit can cause you to lose muscle in addition to fat.
One way to minimise your muscle loss while fasting is to ensure you are eating enough protein on the days you eat.
Additionally, if you are eating small amounts on fast days, including some protein could offer other benefits, including managing your hunger.
Some studies suggest that consuming around 30% of a meal’s calories from protein can significantly reduce your appetite.
Therefore, eating some protein on fast days could help offset some of the fasting side effects.
8. Eat Plenty of Whole Foods on Non-Fasting Days
Most people who fast are trying to improve their health.
Even though fasting involves abstaining from food, it’s still important to maintain a healthy lifestyle on days when you are not fasting.
Home baked cakes without sugar
8oz self raising Flour
4oz vegetable fat suitable for home baking
Half a small cupful of semi skimmed milk
you can add stevia or manuka honey if you prefer your cake to be more sweet.
Electric whisk the mixture until a thick creamy consistency, put mixture in cake tin and oven bake until cooked.
GOOD Foods and teas you can have everyday
green tea, mint tea, lemon tea, hibiscus tea
make sure your soups are low in sugar
tomato soup, minestrone soup, vegetable soup, mushroom soup.
nuts – cashews, walnuts, quinoa, peas, carrot juice, spinach, watercress.
Antioxidants are molecules which can safely interact with free radicals and terminate the chain reaction before vital molecules are damaged. Although there are several enzyme systems within the body that disarm free radicals, the principal antioxidants are vitamin E, beta-carotene, selenium and vitamin C, however it is not good to take too much vitamin C and do not take it regularly, it's water soluble so use the time release and keep it to 1000mg, and only take them to help combat a cold, vitamin C with zinc zaps a cold.
8 health benefits of dandelion tea you may not have known:
Good for Digestion. “Dandelion tea can have many positive effects on your digestive system
Detoxifies the Liver
Acts as a Diuretic
Reduces Water Weight
Powerhouse of Antioxidants
Treats Urinary Tract Infection (UTI)
Stinging Nettle Tea
Studies suggest that it reduces inflammation, hay fever symptoms, blood pressure and blood sugar levels, among other benefits. you can use it as a vegetable the same as you'd have spinach, cooked, pick the leaves near to the top of the plant, one leaf contains around 158 mg Vitamin C, compared to an orange which contains about 58 mg Vitamin C. The herb's diuretic action also flushes excess uric acid from muscles and joints, helping to relieve arthritic pain and act as an anti-inflammatory. Nettle tea is also effective in treating the symptoms of itchy, watery eyes, runny nose and sneezing, common in allergy season. Nettles work very well as a survival food, thanks to their high-quality protein content and high levels of nutrients. At the time of their peak protein content they contain up to 25% protein by dry weight. They are a complete protein, with a good mix of essential amino acids.
The best fruits are the ones that are more sour or yellow, red and bluish-black coloured when ripe: oranges, apricots, grapefruit, tangerines, blackberries, blueberries, black grapes, black plums, strawberries, cherries, yellow-fleshed peaches, pineapple, kiwi, persimmons. The peel or skin contains larger amounts of antioxidants than the pulp. It is also advisable to eat the peel of citrus fruits (only if organic), which is rich in antioxidants. Carrot juice mixed with ginger.
Dark chocolate is rich in flavonoid antioxidants, including it in a well-balanced diet can tackle the cognitive decline, improve brain functions, make the thinking process faster and improve short-term and long-term memory.
Red wine will be richer in phenols abundant in the skin and seeds, such as anthocyanin, proanthocyanidins and flavonols, whereas the phenols in white wine will essentially originate from the pulp, and these will be the phenolic acids together with lower amounts of catechins and stilbenes.
It has been found that people that drink red wine seem less likely to get colds or flu, red wine kills e-coli bacteria, but although it contains antioxidants you really would need to consume over 2000 bottles to benefit from high enough amounts of antioxidants you'd require, however in moderation a glass of wine is good, don't drink too much though as alcohol can also affect your blood pressure.
Chronic drinking can cause liver disease, this adds to the kidney's being overloaded. The rate of blood flow to your kidneys is usually kept at a certain level, so that your kidneys can filter your blood.
MEALS THAT HEAL
Healthy ideas for Evening meals
Steamed: sweet potato, brocolli, cauliflower, carrots, spinach, poached salmon in milk sprinkled with tarragon.
Laqucia World QUICK Meals
Mushroom and mycoprotein Curry
All types of edible mushrooms contain protein and fibre. They also contain B vitamins as well as a powerful antioxidant called selenium, which helps to support the immune system and prevent damage to cells and tissues. Nutritional benefits of eating mushrooms. You can't go wrong with mushrooms. They're fat-free, low-sodium, low-calorie, and cholesterol-free. They're also packed with fibre, vitamins, and minerals.
It’s easy to make the mistake of thinking that ‘plant-based’ automatically means healthy, but the same rules apply to plant products as they do to animal products, the less processed the better. Quorn is made by fermenting Fusarium venenatum, a natural fungus found in soil. Glucose, oxygen, nitrogen and minerals are added to create the conditions for it to convert wheat into protein. There is no denying that it’s a highly processed food. If you fancy a meat substitute every now and then, Quorn is fine.
Quick, easy and healthy method: Fry your onions and garlic in Extra-virgin olive oil, then add your mushrooms. Place mycoprotein pieces in microwave bowl with low fat curry sauce, with added turmeric, cayenne pepper, for five minutes, then add to and stir in with your mushrooms in pan and simmer for a further two minutes. Place your packet of microwave rice in microwave for two minutes, and you're ready to serve up your meal.
In 1982, the National Academy of Sciences presented basic dietary recommendations for preventing cancer, which subsequently have been strongly supported by research.
Here are the five points of their anti-cancer diet strategy and ways to incorporate it into your daily routine.
1. decrease the amount of fat in your diet.
2. increase the amount of fibre in your diet.
3. avoid obesity
4. drink alcohol in moderation, if at all.
5. minimise consumption of salt-cured, pickled and smoked foods.
CHECKING YOUR CHOLESTEROL
If you test in the borderline-high range (200-239 milligrams per deciliter), the AHA suggests having a second test and averaging the two results. If you're still in the risk group, take actions to change your eating habits.
For those with a level of 240 or higher, medical supervision is advised.
If your cholesterol level is at a desireable range (below 200 mg/dl), the Natuional Heart, Lung, and Blood Institute says to be re-tested every five years or less.
HDL AND LDL
After your cholesterol blood test, you'll be given figures for your total cholesterol, your LDL and your HDL.
The LDL is primarily a mixture of cholesterol and protein that the blood carries to all parts of the body. The body needs some cholesterol for everyday functions like producing hormones and digestive acids. LDL is often called the "bad cholesterol."
So you need a low LDL and a high HDL. Your LDL should be below 130 mg/dl; and your HDL should be above 35 mg/dl and your total cholesterol should be below 200 mg/dl.
Saturated Fat index (CSI) The lower the CSI number the more healthy the food.
BREAKFAST AT LAQUCIA WORLD
Organic porridge oats with oat-bran, pear, grapes, blueberries, clementines, excellent in the mornings, oats are among the healthiest grains on earth. They're a gluten-free whole grain and a great source of important vitamins, minerals, fibre and antioxidants. Studies show that oats and oatmeal have many health benefits. These include weight loss, lower blood sugar and a reduced risk of heart disease.
LUNCH AT LAQUCIA WORLD
Watercress and spinach, Avocado, Tomato, Black Grapes, Cucumber, Couscous with Peppers, Chickpeas and Cranberries, Olives stuffed with Garlic.
live Oil, Organic Apple Cider Vinegar, Turmeric, Cayenne Pepper, Freshly Squeezed Lemon Juice, Pinch of Black Pepper. Helps reduce clogging of the arteries, the buildup of cholesterol and fatty deposits called plaques on the inner walls of the arteries.
All the Benefits of Turmeric Lemon and lime. Turmeric, known as Indian saffron, has anti-inflammatory properties and boosts the immune system. For a stronger cleansing effect, add a teaspoon of turmeric to your healthy decoction of hot water, lemon juice, lime and ginger in the morning.
Good health and well being is not just about good food, it's about your life style, a combination of different activities that all in their own way possess vital benefits.
Meditation, the mind, heart, and body can improve with regular meditation. Most people aren't raised to sit and say "Om." But meditation has gained millions of converts, helping them ease chronic pain, anxiety, stress, improve heart health, boost mood and immunity, and resolve pregnancy problems.
When we train in meditation, our mind will become more and more peaceful. When the turbulence of our mental busyness subsides and our mind becomes still, a deep contentment naturally will arise from within. Focusing your mind on the sensation of your breath for fifteen minutes a day will help you to reduce stress in everyday life.
Along with walking, many examples of mild exercise form part of common daily routines. For example, walking up stairs is usually a mild exercise. Leisure activities, such as cycling, canoeing, swimming or dancing, also offer mild workouts, provided you practice them at a low to moderate intensity.
Sleep makes you feel better, but its importance goes way beyond just boosting your mood or banishing under-eye circles. Adequate sleep is a key part of a healthy lifestyle, and can benefit your heart, weight, mind, and more; Here are some health benefits researchers have discovered about a good night's sleep.
Research shows that consistently getting seven to eight hours of sleep per night is beneficial. Any more or less can increase your risk for serious conditions like diabetes, heart disease, and even death. Getting enough quality sleep is also key to a healthy lifestyle.
A 45-minute catnap helps lower blood pressure american researchers reported last week. They said a daytime snooze could improve heart health, particularly if you're not getting as much sleep as you should at night; The theory is that napping, by encouraging you to relax, reduces blood pressure.
Typically, Growth Hormone levels usually deplete by 50% after the age of 70 sermorelin stimulates regrowth and regeneration of the pituitary gland to secrete more growth hormone. An added benefit is that it also promotes slow wave sleep (deep sleep).
At the Longevity institute in California, growth hormones have been found to shorten lifespan, thus shorter people on average seem to live longer, moreover they do say the fast mimicking diet helps to imitate similar chemical balance characteristics found naturally in shorter people; this will in turn help taller people giving them added benefits to fight disease in older age.
Normal body functions, such as breathing or physical activity, and other lifestyle habits (such as smoking) produce substances called free radicals that attack healthy cells. When these healthy cells are weakened, they are more susceptible to cardiovascular disease and certain types of cancers.
Common antioxidants include:
Dr David Sinclaire one of the World's leading scientists from Harvard University researching longevity, in a recent interview said, to reverse your ageing clock, he personally takes the following supplements, because over many years of research he's discovered not just biologically but genetically, the following supplements seem to assist in the process of resetting your ageing clock to be youthful again.
Metformin (Metformin hydrochloride) is a type of medicine known as a biguanide. This works to lower the amount of sugar in the blood of people with diabetes. It does this by lowering the amount of sugar produced in the liver, and also increasing the sensitivity of muscle cells to insulin.
Metformin, recommended dosage
1 gram taken with the evening meal, however it is important to note, people who take it for longevity who are not diabetic must take it when the body is at rest, and not when you are exercising.
Nicotinamide adenine dinucleotide (NAD+) is one of the most important and interesting molecules in the body. It is required for over 500 enzymatic reactions and plays key roles in the regulation of almost all major biological processes (Ansari and Raghava)
The foods most enriched in nicotinamide riboside are not well identified, although yeast-containing food products are presumed natural sources of the compound and milk-derived products such as whey fractions have been reported to contain the nutrient.
Nicotinamide Mononucleotide is a safe and naturally occurring molecule metabolite already found in the body, but is depleted as we age. NMN is a direct and powerful (Nicotinamide Adenine Dinucleotide) NAD+ supplement.
Nicotinamide mononucleotide (NMN) or Nicotinamide-1-ium-1-β-D-ribofuranoside 5′-phosphate is a type of bio-active nucleotide which is naturally formed by the reaction between a phosphate group and a nucleoside containing ribose and nicotinamide, Generally, it exists in two anomeric forms namely alpha and beta.
Apples promote heart health in several ways. They're high in soluble fibre, which helps lower cholesterol. They also have polyphenols, which are linked to lower blood pressure and stroke risk.